PE/Cyanine7 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL0504)

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SKU:
AGEL0504
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
M5/114
Conjugation:
PE/Cy7
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The Mouse MHC II (I-A/I-E) Monoclonal Antibody (PE/Cyanine7 Conjugated) is a specialized reagent designed for the detection of major histocompatibility complex class II molecules in mouse samples. This monoclonal antibody, clone M5/114, is conjugated with PE/Cyanine7 for optimal fluorescent signal detection in flow cytometry and microscopy applications.MHC II molecules play a key role in the immune system by presenting antigens to CD4+ T cells, triggering the adaptive immune response. The specificity and high reactivity of this antibody make it a valuable tool for studying antigen presentation, T cell activation, and immune responses in mouse models.

With its validated performance and application versatility, the Mouse MHC II (I-A/I-E) Monoclonal Antibody (PE/Cyanine7 Conjugated) is essential for immunology research, vaccine development, and investigations into immune-related diseases. Unlock the potential of your studies with this reliable and precise antibody designed to enhance your research outcomes.

Product Title:PE/Cyanine7 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL0504
Size:25µg, 100µg
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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