PE/Cyanine7 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL0495)

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SKU:
AGEL0495
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
M5/114
Conjugation:
PE/Cy7
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The Mouse MHC II (I-A/I-E) Monoclonal Antibody PE/Cyanine7 Conjugated (M5/114) (AGEL0495) offered by Assay Genie is a powerful tool for studying the Major Histocompatibility Complex (MHC) II molecules in mouse samples. This antibody, conjugated with PE/Cyanine7, is specifically designed to target the I-A and I-E isoforms of MHC II, allowing for precise and detailed analysis in flow cytometry and other immunological assays.MHC II molecules play a crucial role in the adaptive immune response by presenting antigens to CD4+ T cells, thereby initiating specific immune reactions. The M5/114 antibody binds specifically to the I-A and I-E isoforms, enabling researchers to identify and study antigen-presenting cells, monitor immune responses, and investigate immune-related disorders in mouse models.

With its high specificity and efficiency, the Mouse MHC II (I-A/I-E) Monoclonal Antibody PE/Cyanine7 Conjugated (M5/114) (AGEL0495) from Assay Genie is a valuable tool for immunologists, researchers, and scientists studying the intricate mechanisms of the immune system in mouse models. By facilitating the identification and analysis of MHC II molecules, this antibody contributes to advancing our understanding of immune responses, immunotherapy, and autoimmune diseases in preclinical research settings.

Product Title:PE/Cyanine7 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL0495
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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