PE/Cyanine5 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL0503)

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SKU:
AGEL0503
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
M5/114
Conjugation:
PE/Cy5
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The Mouse MHC II (I-A/I-E) Monoclonal Antibody PE-Cyanine5 Conjugated (M5/114) is a highly specific antibody designed for research involving major histocompatibility complex class II (MHC II) molecules in mice. This monoclonal antibody, conjugated with PE-Cyanine5, is ideal for flow cytometry applications, enabling the detection and analysis of MHC II (I-A/I-E) expression on various immune cell populations.MHC class II molecules play a crucial role in the presentation of antigens to CD4+ T cells, initiating adaptive immune responses. The M5/114 antibody specifically recognizes the I-A and I-E subtypes of MHC class II molecules in mice, allowing researchers to study antigen presentation, immune cell activation, and immune response regulation in experimental models.

This monoclonal antibody is a valuable tool for immunologists, researchers, and scientists studying immune responses, autoimmune diseases, infection, and vaccination in mouse models. The PE-Cyanine5 conjugation provides additional flexibility for multicolor flow cytometry experiments, facilitating in-depth analysis of MHC II expression patterns in complex immune cell populations.By using the Mouse MHC II (I-A/I-E) Monoclonal Antibody PE-Cyanine5 Conjugated (M5/114), researchers can gain valuable insights into the role of MHC II molecules in immune surveillance, immune activation, and immune-mediated diseases, leading to advancements in immunotherapy, vaccine development, and our understanding of immune system function in health and disease.

Product Title:PE/Cyanine5 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL0503
Size:25µg, 100µg
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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