The Mouse LY-6G Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, 1A8) is a vital tool for researchers investigating immune responses in mouse models. This monoclonal antibody specifically targets LY-6G, a cell surface marker found on neutrophils and myeloid-derived suppressor cells. With its PerCP-Cyanine5.5 conjugation, this antibody allows for accurate and sensitive detection of LY-6G expression in flow cytometry and immunofluorescence applications.LY-6G is a crucial marker for identifying and characterizing neutrophils, which are central players in the innate immune response against infections and inflammation. Additionally, myeloid-derived suppressor cells, characterized by LY-6G expression, have immunosuppressive capabilities that impact autoimmune diseases, cancer progression, and inflammatory conditions.
By targeting LY-6G, researchers can gain insights into the function and dynamics of these immune cell populations in various experimental contexts.This Mouse LY-6G Monoclonal Antibody offers high specificity and sensitivity, enabling precise quantification and phenotypic analysis of LY-6G-expressing cells in mouse samples. Its use is instrumental in advancing research related to immunology, inflammation, infection, and cancer, providing valuable data for understanding immune cell dynamics and developing targeted therapies.
Product Title:
PerCP/Cyanine5.5 Anti-Mouse Ly6G Antibody [1A8]
SKU:
AGEL1382
Size:
25µg, 100µg
Clone No:
1A8
Synonyms:
Lymphocyte antigen 6G;Ly-6G;Ly-6G.1;Ly6g;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P35461
Gene ID:
546644
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Lymphocyte antigen 6 complex, locus G (Ly-6G), a 21-25 kD GPI-anchored protein, is expressed on the majority of myeloid cells in bone marrow and peripheral granulocytes.
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