The Mouse Ly6G Monoclonal Antibody, PerCP Conjugated (1A8) (AGEL1378) is a powerful tool for researchers studying immune cells and inflammation in mouse models. This monoclonal antibody specifically targets Ly6G, a marker expressed on neutrophils and myeloid-derived suppressor cells. By conjugating with PerCP, this antibody allows for efficient flow cytometry analysis and cell sorting, enabling precise identification and quantification of Ly6G-positive cells in complex biological samples.Ly6G is a critical marker for identifying neutrophils, the most abundant white blood cells in the immune system, and myeloid-derived suppressor cells, which play a role in regulating immune responses.
By targeting Ly6G, researchers can gain insights into the dynamics of neutrophil recruitment and function in various disease states, including infections, inflammatory disorders, and cancer. The use of this antibody in flow cytometry applications provides a valuable tool for investigating the role of Ly6G-expressing cells in immune responses and disease pathogenesis in mouse models, paving the way for a deeper understanding of immune cell dynamics and potential therapeutic targets.
Product Title:
PerCP Anti-Mouse Ly6G Antibody [1A8]
SKU:
AGEL1378
Size:
25µg, 100µg
Clone No:
1A8
Synonyms:
Lymphocyte antigen 6G;Ly-6G;Ly-6G.1;Ly6g;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PerCP Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P35461
Gene ID:
546644
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Lymphocyte antigen 6 complex, locus G (Ly-6G), a 21-25 kD GPI-anchored protein, is expressed on the majority of myeloid cells in bone marrow and peripheral granulocytes.