The Mouse Ly6C Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (MONTS-1) is an essential tool for immunology research, particularly in the study of Ly6C, a key marker for monocyte subset identification. This antibody, derived from hybridomas, exhibits high specificity for mouse samples and is validated for flow cytometry applications. It recognizes the Ly6C protein, facilitating precise detection and analysis in diverse cell populations, making it well-suited for investigations in immunology, inflammation, and related fields.
Ly6C, a glycosylphosphatidylinositol-anchored protein, is crucial for immune cell differentiation and response regulation. Its involvement in various inflammatory processes underscores its significance as a biomarker for monitoring immune activation and disease progression. Researchers can utilize this antibody to explore the role of Ly6C in conditions such as infection, autoimmunity, and tissue damage, enhancing understanding of immune mechanisms and potential therapeutic targets.
Lymphocyte antigen 6 complex; locus C;Ly 6C;Ly6c1;Ly6c2;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P0CW03
Gene ID:
17067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Most hematopoietic cells express one or more members of Ly-6 family. The expression of Ly-6 varies with development stage and activation. Ly-6C is a 14-17 kD GPI-linked surface protein expressed on mouse monocyte/macrophage cells, endothelial cells, neutrophils, and some T cell subsets. Ly-6C is reported to be an indicator of memory CD8+ T cells.