PE Anti-Mouse Ly6A/E(Sca-1) Antibody [D7] (AGEL2003)

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SKU:
AGEL2003
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE Anti-Mouse Ly6A/E(Sca-1) Antibody [D7]

The Mouse Ly6a/E Sca-1 Monoclonal Antibody (PE-conjugated) is a powerful tool for researchers studying stem cell populations and immune cell differentiation. Sca-1, also known as Ly6a, is a cell surface marker commonly used for identifying and isolating hematopoietic stem cells and other progenitor cell populations in mice.This monoclonal antibody, conjugated with phycoerythrin (PE), provides a fluorescent signal for flow cytometry and cell sorting applications. By specifically binding to the Sca-1/Ly6a protein, this antibody enables precise identification and characterization of stem cells and subsets of immune cells in complex cell populations.

Researchers in the fields of stem cell biology, immunology, and developmental biology can benefit from the use of this antibody to investigate the roles of Sca-1-expressing cells in tissue regeneration, immune response modulation, and disease progression. With its high specificity and sensitivity, this antibody is an essential tool for advancing our understanding of stem cell biology and immune system function in various research settings.

Product Title:PE Anti-Mouse Ly6A/E(Sca-1) Antibody [D7]
SKU:AGEL2003
Size:25µg, 100µg
Clone No:D7
Synonyms:Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05533
Gene ID:110454
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

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