APC Anti-Mouse Ly6A/E(Sca-1) Antibody [D7] (AGEL2004)

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SKU:
AGEL2004
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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APC Anti-Mouse Ly6A/E(Sca-1) Antibody [D7]

The Mouse LY6A/E (Sca-1) Monoclonal Antibody (APC-conjugated) d7-AGEL2004 is a valuable tool for researchers studying immune cell markers and stem cell biology. This monoclonal antibody, derived from hybridoma cells, specifically targets the LY6A/E (Sca-1) protein, a marker associated with stem cells, hematopoietic progenitors, and activated T cells.LY6A/E, also known as stem cell antigen-1 (Sca-1), is a cell surface glycoprotein commonly used to identify stem and progenitor cells in various tissues, including the bone marrow and peripheral blood. Its expression has been linked to developmental processes, immune responses, and cancer biology. The APC conjugation of this antibody enables its use in flow cytometry applications, allowing for precise identification and quantification of LY6A/E-positive cells within complex cell populations.

By utilizing the Mouse LY6A/E (Sca-1) Monoclonal Antibody (APC-conjugated) d7-AGEL2004, researchers can further explore the roles of LY6A/E in stem cell maintenance, immune cell regulation, and disease pathogenesis. This antibody offers a reliable tool for investigating the molecular mechanisms and functional significance of LY6A/E in various biological contexts, paving the way for new insights and potential therapeutic targets in stem cell research and immunology.

Product Title:APC Anti-Mouse Ly6A/E(Sca-1) Antibody [D7]
SKU:AGEL2004
Size:25µg, 100µg
Clone No:D7
Synonyms:Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05533
Gene ID:110454
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

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