PerCP/Cyanine5.5 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL1486)

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SKU:
AGEL1486
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
RB6-8C5
Conjugation:
PerCP/Cy5.5
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The Mouse LY-6G/LY-6C (Gr-1) Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, RB6-8C5) is a valuable tool for researchers studying the immune system and inflammation in mice. This antibody, designated AGEL1486, targets the LY-6G/LY-6C (Gr-1) protein complex, which is commonly used as a marker for certain subsets of immune cells, such as granulocytes and myeloid-derived suppressor cells.The RB6-8C5 antibody is monoclonal in origin, offering high specificity and reliable performance in applications such as flow cytometry and immunofluorescence. By binding to the LY-6G/LY-6C (Gr-1) antigen, this antibody enables researchers to accurately identify and quantify these cell populations in various tissues and experimental conditions.

Given the crucial roles of LY-6G/LY-6C (Gr-1) cells in the immune response, this antibody is instrumental for investigating inflammatory processes, infection responses, and the tumor microenvironment in murine models. Its application extends to preclinical studies aiming to elucidate the mechanisms underlying immune cell dynamics and their impact on disease progression and treatment outcomes.

Product Title:PerCP/Cyanine5.5 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL1486
Size:25µg, 100µg
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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