The Mouse LY-6G/LY-6C (Gr-1) Monoclonal Antibody (perCP Conjugated, RB6-8C5) is a valuable tool for researchers studying immune cell populations in mouse models. This antibody, provided by Assay Genie, is specifically designed for detecting LY-6G/LY-6C (Gr-1), a marker commonly used to identify neutrophils and inflammatory monocytes.The RB6-8C5 antibody is conjugated to perCP (peridinin-chlorophyll-protein complex) for easy detection and analysis by flow cytometry, making it a reliable choice for immunophenotyping experiments. With its high specificity and sensitivity, this monoclonal antibody enables precise identification and characterization of Gr-1 positive cell populations in various tissues and immune responses.
Furthermore, the LY-6G/LY-6C (Gr-1) antibody is crucial for studying inflammatory processes, such as infection, autoimmunity, and cancer, where neutrophils and monocytes play significant roles. By targeting the Gr-1 marker, researchers can gain insights into the dynamics of immune cell recruitment, activation, and function in different disease contexts, paving the way for developing new therapeutic strategies and understanding immune-mediated pathologies.Order the Mouse LY-6G/LY-6C (Gr-1) Monoclonal Antibody (perCP Conjugated, RB6-8C5) from Assay Genie today to enhance your research in immunology, inflammation, and disease models in mouse studies.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P35461 P0CW03
Gene ID:
546644 ,17067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.