The Mouse LY-6G/LY-6C (GR-1) Monoclonal Antibody APC Conjugated (RB6-8C5) is a powerful tool for researchers investigating immune cell populations in mice. This monoclonal antibody specifically targets the LY-6G/LY-6C (GR-1) protein, a cell surface marker commonly used to identify neutrophils and inflammatory monocytes.With its APC conjugation, this antibody is ideal for flow cytometry applications, enabling precise and efficient analysis of immune cell populations in experimental mouse models. The RB6-8C5 antibody has been rigorously validated for its specificity and sensitivity, ensuring reliable and reproducible results in research studies focusing on inflammation, infection, and immune responses.
By utilizing the Mouse LY-6G/LY-6C (GR-1) Monoclonal Antibody APC Conjugated (RB6-8C5), researchers can gain insights into the dynamics of immune cell populations in various disease and experimental settings. This antibody is a valuable tool for enhancing our understanding of immune system regulation and responses, opening new avenues for exploring therapeutic strategies in immunology and related fields.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35461 P0CW03
Gene ID:
546644 ,17067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.