Mouse Lumican/LUM Recombinant Protein (RPES1266)
- SKU:
- RPES1266
- Product type:
- Recombinant Protein
- Host species:
- Human Cells
- Reactivity:
- Mouse
Frequently bought together:
Description
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Mouse Lumican/LUM Recombinant Protein
Keratan sulfate proteoglycan lumican, mostly known as lumican, belongs to the SLRP class II subfamily and the small leucine-rich proteoglycan (SLRP) family. Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production. Lumican is expressed in a variety of tissues, including skin, artery, lung, cornea, kidney, bone, aorta, and articular cartilage. The abnormal connective tissue phenotype seen in the Lumican null mice shows the importance of the role of Lumican in collagen fibrillogenesis. In addition to the control of collagen fibril assembly, Lumican has been shown to play a role in the regulation of cell proliferation, migration, and adhesion.
| Product Name: | Mouse Lumican/LUM Recombinant Protein (RPES1266) |
| Product Code: | RPES1266 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | Keratan sulfate proteoglycan lumican,KSPG lumican,Lumican, LDC |
| Accession: | P51885 |
| Sequence: | Gln19-Asn338 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Lumican is produced by our Mammalian expression system and the target gene encoding Gln19-Asn338 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 37.4 kDa |
| AP Mol Mass: | 40-60 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS,pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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