Mouse LGALS9 Recombinant Protein (RPPB0291)
- SKU:
- RPPB0291
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Mouse
- Target:
- LGALS9
- Synonyms:
- Galectin-9
- Gal-9
- Lgals9
- Lgals5
- Source:
- Escherichia Coli
- Uniprot:
- O08573
Description
| Product Name: | Mouse LGALS9 Recombinant Protein |
| Product Code: | RPPB0291 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | LGALS9 |
| Synonyms: | Galectin-9, Gal-9, Lgals9, Lgals5, LGALS35, AA407335, AI194909, AI265545. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The LGALS9 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMALFSAQ SPYINPIIPF TGPIQGGLQE GLQVTLQGTT KSFAQRFVVN FQNSFNGNDI AFHFNPRFEE GGYVVCNTKQ NGQWGPEERK MQMPFQKGMP FELCFLVQRS EFKVMVNKKF FVQYQHRVPY HLVDTIAVSG CLKLSFITFQ TQNFRPAHQA PMAQTTIHMV HSTPGQMFST PGIPPVVYPT PAYTIPFYTP IPNGLYPSKS IMISGNVLPD ATRFHINLRC GGDIAFHLNP RFNENAVVRN TQINNSWGQE ERSLLGRMPF SRGQSFSVWI ICEGHCFKVA VNGQHMCEYY HRLKNLQDIN TLEVAGDIQL THVQT |
LGLAS9 binds galactosides and has high affinity for the Forssman pentasaccharide. LGLAS9 participates in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. LGLAS9 is a ligand for HAVCR2/TIM3. LGLAS9 Induces T-helper type 1 lymphocyte (Th1) death. LGLAS9 performs as an eosinophil chemoattractant LGLAS9 is an S-type lectin which is over-expressed in Hodgkin's disease tissue and takes part in the interaction between the H&RS cells with their surrounding cells.
LGALS9 mouse Recombinant produced E. coli is a single polypeptide chain containing 345 amino acids (1-322) and having a molecular mass of 38kDa.LGALS9 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | galectin-9: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Cellular Component: cytoplasm; extracellular region Molecular Function:galactoside binding; carbohydrate binding Biological Process: heterophilic cell adhesion |
| UniProt Code: | O08573 |
| NCBI GenInfo Identifier: | 226531139 |
| NCBI Gene ID: | 16859 |
| NCBI Accession: | NP_001152773.1 |
| UniProt Related Accession: | O08573 |
| Molecular Weight: | |
| NCBI Full Name: | galectin-9 isoform 2 |
| NCBI Synonym Full Names: | lectin, galactose binding, soluble 9 |
| NCBI Official Symbol: | Lgals9 |
| NCBI Official Synonym Symbols: | gal-9; Lgals5; LGALS35; AA407335; AI194909; AI265545; galectin-9 |
| NCBI Protein Information: | galectin-9 |
| UniProt Protein Name: | Galectin-9 |
| Protein Family: | Gallinacin |
| UniProt Gene Name: | Lgals9 |
| UniProt Entry Name: | LEG9_MOUSE |
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