Mouse LGALS8 Recombinant Protein (RPPB0289)
- SKU:
- RPPB0289
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Mouse
- Target:
- LGALS8
- Synonyms:
- Galectin-8
- Gal-8
- LGALS-8
- AI326142
- Source:
- Escherichia Coli
- Uniprot:
- Q9JL15
Description
| Product Name: | Mouse LGALS8 Recombinant Protein |
| Product Code: | RPPB0289 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | LGALS8 |
| Synonyms: | Galectin-8, Gal-8, LGALS-8, AI326142, D13Ertd524e, 1200015E08Rik. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The LGALS8 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMLSLNNL QNIIYNPIIP YVGTITEQLK PGSLIVIRGH VPKDSERFQV DFQLGNSLKP RADVAFHFNP RFKRSSCIVC NTLTQEKWGW EEITYDMPFR KEKSFEIVFM VLKNKFQVAV NGRHVLLYAH RISPEQIDTV GIYGKVNIHS IGFRFSSDLQSMETSALGLT QINRENIQKP GKLQLSLPFE ARLNASMGPG RTVVIKGEVN TNARSFNVDL VAGKTRDIAL HLNPRLNVKA FVRNSFLQDA WGEEERNITC FPFSSGMYFE MIIYCDVREF KVAINGVHSL EYKHRFKDLS SIDTLSVDGD IRLLDVRSW |
| Biological Activity: | The ED50 for this effect is ? 2ug/ml. Measured by its ability to agglutinate human red blood cells. |
LGALS8 is a prostate-specific antigen that is solely overexpressed in malignant tumors and thus is a supplementary specific identifier of malignancies. LGALS8 is part of the galectin gene family which facilitates both cell-cell and cell matrix interactions in a method parallel to the selectin subgroup of C-type lectins.
LGALS8 mouse Recombinant produced E. coli is a single polypeptide chain containing 339 amino acids (1-316) and having a molecular mass of 38kDa.LGALS8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | galectin-8: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion Chromosomal Location of Human Ortholog: 13 A1|13 4.64 cM Cellular Component: cytoplasm; cytoplasmic vesicle; cytosol; membrane Molecular Function:carbohydrate binding; integrin binding Biological Process: autophagy; plasma cell differentiation; T cell costimulation |
| UniProt Code: | Q9JL15 |
| NCBI GenInfo Identifier: | 312261230 |
| NCBI Gene ID: | 56048 |
| NCBI Accession: | NP_001185972.1 |
| UniProt Related Accession: | Q9JL15 |
| Molecular Weight: | 36,162 Da |
| NCBI Full Name: | galectin-8 isoform 1 |
| NCBI Synonym Full Names: | lectin, galactose binding, soluble 8 |
| NCBI Official Symbol: | Lgals8 |
| NCBI Official Synonym Symbols: | Lgals-8; AI326142; D13Ertd524e; 1200015E08Rik |
| NCBI Protein Information: | galectin-8 |
| UniProt Protein Name: | Galectin-8 |
| UniProt Synonym Protein Names: | LGALS-8 |
| Protein Family: | Gallinacin |
| UniProt Gene Name: | Lgals8 |
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