The Mouse IL-6 Monoclonal Antibody (APC-conjugated, MP5-20F3, AGEL2072) is a high-quality research tool designed for investigating interleukin-6 (IL-6), a key cytokine involved in immune response and inflammation. This antibody, specially formulated for flow cytometry applications, offers superior detection and specificity for IL-6, a crucial protein in various physiological processes.IL-6 is a multifunctional cytokine with diverse roles in inflammation, hematopoiesis, and immune regulation. Its dysregulation is associated with various diseases, including autoimmune disorders, cancer, and inflammatory conditions.
The APC-conjugated monoclonal antibody specifically targets IL-6, allowing precise detection and quantitative analysis in cell samples.Researchers in immunology, oncology, and inflammation-related fields can benefit from the use of this antibody to study the expression and activity of IL-6 in different cell types and disease models. By understanding the role of IL-6 in immune modulation and disease pathogenesis, novel therapeutic strategies targeting IL-6 signaling pathways may be developed for potential clinical applications.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08505
Gene ID:
16193
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. IL-6 plays a role in host defense, acute phase reactions, immune responses, and hematopoiesis. IL-6 is expressed by T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes.