The Mouse IL-10 Monoclonal Antibody FITC Conjugated (JES5-16E3) is a specialized tool for research purposes, particularly in the field of immunology. This antibody, available at AssayGenie, is meticulously designed to target and bind to the mouse IL-10 protein, allowing for precise identification and analysis in diverse cell populations.IL-10, a cytokine with potent immunosuppressive properties, plays a crucial role in regulating immune responses and maintaining immune balance. By targeting IL-10, researchers can delve deeper into its function and implications in various diseases, including autoimmune disorders, inflammation, and infections.
The FITC conjugation of this monoclonal antibody enhances its utility by enabling fluorescence-based detection methods, facilitating visualization and localization studies. This feature makes it a valuable asset for experiments requiring high sensitivity and specificity in detecting IL-10 in mouse samples.Researchers and scientists engaged in immunology, inflammation, and related fields will find the Mouse IL-10 Monoclonal Antibody FITC Conjugated (JES5-16E3) from AssayGenie to be an indispensable tool for their studies, contributing to a better understanding of immune regulation and potential therapeutic interventions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P18893
Gene ID:
16153
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production); and promotes mast cell proliferation in combination with IL-4.