Mouse IgG Recombinant Protein (RPPB3749)
- SKU:
- RPPB3749
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Mouse
- Target:
- IgG
- Synonyms:
- Ig gamma-2A chain C region
- A allele
- Immunoglobulin heavy chain gamma polypeptide
- Ighg
- Source:
- Hi-5 cells
- Uniprot:
- P01863
Description
| Product Name: | Mouse IgG Recombinant Protein |
| Product Code: | RPPB3749 |
| Size: | 20µg |
| Species: | Mouse |
| Target: | IgG |
| Synonyms: | Ig gamma-2A chain C region, A allele, Immunoglobulin heavy chain gamma polypeptide, Ighg, Igh-1, Igh-1a, 1810060O09Rik. |
| Source: | Hi-5 cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | IgG protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | ADPEPRGPTI KPCPPCKCPA PNLLGGPSVF IFPPKIKDVL MISLSPIVTC VVVDVSEDDP DVQISWFVNN VEVHTAQTQT HREDYNSTLR VVSALPIQHQ DWMSGKEFKC KVNNKDLPAP IERTISKPKG SVRAPQVYVL PPPEEEMTKK QVTLTCMVTD FMPEDIYVEW TNNGKTELNY KNTEPVLDSD GSYFMYSKLR VEKKNWVERN SYSCSVVHEG LHNHHTTKSF SRTPGKHHHH HH |
Immunoglobulin G (IgG) are antibody molecules. Each IgG is composed of four peptide chains - 2 heavy chains g and 2 light chains. Also, each IgG has 2 antigen binding sites. IgG antibodies are involved in primarily the secondary immune response. The presence of specific IgG, generally, relates to maturation of the antibody response. IgG also has an imperative role in Antibody-dependent cell-mediated cytotoxicity (ADCC) and Intracellular antibody-mediated proteolysis, in which it binds to TRIM21 (the receptor with greatest affinity to IgG in humans) in order to direct marked virions to the proteasome in the cytosol.
IgG Mouse Recombinant produced in Hi-5 cells is a single polypeptide chain containing 242 amino acids (98-330 a.a) and having a molecular mass of 27.5kDa.IgG is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
| UniProt Code: | P01863 |
| NCBI GenInfo Identifier: | 121048 |
| NCBI Gene ID: | 380793 |
| NCBI Accession: | P01863.1 |
| UniProt Related Accession: | P01863,P01864,P01865,P84751 |
| Molecular Weight: | 36,389 Da |
| NCBI Full Name: | Ig gamma-2A chain C region, A allele |
| NCBI Synonym Full Names: | immunoglobulin heavy constant gamma 2A |
| NCBI Official Symbol: | Ighg2a |
| NCBI Official Synonym Symbols: | Igh-1; Igh-1a; 1810060O09Rik |
| UniProt Protein Name: | Ig gamma-2A chain C region, A allele |
| UniProt Synonym Protein Names: | Immunoglobulin heavy chain gamma polypeptide |
| UniProt Gene Name: | Ighg |
| UniProt Entry Name: | GCAA_MOUSE |
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