GenieFluor 488 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL0025)

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SKU:
AGEL0025
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
M5/114
Conjugation:
AF 488
Applications:
FC
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The GenieFluor 488 Conjugated Mouse I-A/I-E Monoclonal Antibody (M5/114) is specifically designed for research involving I-A/I-E, essential molecules within the Major Histocompatibility Complex (MHC) class II system that play a crucial role in antigen presentation and activation of immune responses. This monoclonal antibody, produced in mice, is highly specific to mouse I-A/I-E and validated for use in flow cytometry applications. Its conjugation with GenieFluor 488 ensures bright and stable green fluorescence, enabling precise and reliable detection.I-A/I-E molecules are fundamental to the adaptive immune response, facilitating the presentation of antigens to CD4+ T cells. Their critical function in immune regulation makes them valuable targets for research into autoimmune disorders, chronic inflammatory conditions, and infectious diseases.

The GenieFluor 488 Conjugated Mouse I-A/I-E Monoclonal Antibody (M5/114) is an indispensable tool for researchers seeking to uncover the mechanisms of antigen presentation and develop therapies that modulate immune function.By providing accurate and sensitive detection of I-A/I-E molecules, this antibody supports comprehensive studies of immune response pathways, contributing to the advancement of therapeutic strategies for autoimmune diseases and other immune-related conditions. Understanding the activity of I-A/I-E is crucial for creating innovative immunotherapies that leverage or modulate antigen presentation in various disease contexts. This antibody is essential for advancing the fields of immunology and cancer research.

Product Title:GenieFluor 488 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL0025
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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