PerCP/Cyanine5.5 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1279)

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SKU:
AGEL1279
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
IM7
Conjugation:
PerCP/Cy5.5
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse/Human CD44 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated) (IM7) is a versatile tool for immunological research applications involving the CD44 cell surface glycoprotein. This antibody, conjugated with PerCP-Cyanine5.5 for fluorescent detection, recognizes CD44 in both mouse and human samples with high specificity. It is validated for use in flow cytometry and immunofluorescence techniques, facilitating accurate and reliable detection of CD44 expression in various cell types.CD44 is a multifunctional cell adhesion molecule involved in processes such as cell migration, adhesion, and signaling, making it a crucial target in studies related to inflammation, cancer metastasis, and stem cell biology. The IM7 antibody specifically binds to CD44, allowing for the identification and characterization of CD44-expressing cells in experimental settings.

Its sensitivity and specificity make it an ideal choice for researchers investigating the role of CD44 in health and disease.By leveraging the IM7 Monoclonal Antibody, researchers can gain valuable insights into the functions and regulations of CD44, paving the way for advancements in therapeutic interventions targeting CD44-associated pathways. Whether studying immune cell interactions, tumor microenvironment dynamics, or stem cell properties, this antibody provides a reliable tool for exploring the complex biology of CD44 and its implications in various physiological and pathological contexts.

Product Title:PerCP/Cyanine5.5 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1279
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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