PE/Cyanine7 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1277)

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SKU:
AGEL1277
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse/Human CD44 Monoclonal Antibody (PE/Cyanine7 Conjugated) is a highly specific and versatile tool for researchers studying CD44, a cell surface glycoprotein involved in cell adhesion, migration, and signaling. This antibody, offered by AssayGenie, is conjugated with PE/Cyanine7 for easy visualization and detection in flow cytometry applications. CD44 is known for its diverse functions in various biological processes, including lymphocyte activation, tumor metastasis, and inflammation. By targeting CD44 with this monoclonal antibody, researchers can accurately identify and analyze CD44-expressing cells in both mouse and human samples.

This makes it a valuable tool for investigating the role of CD44 in cancer biology, stem cell research, and immunology.The specificity and sensitivity of this monoclonal antibody, combined with the convenience of the PE/Cyanine7 conjugation, make it an essential component for studies aiming to elucidate the complex mechanisms involving CD44. Whether exploring tumor microenvironments, immune cell interactions, or stem cell differentiation, this antibody provides reliable and reproducible results for researchers in diverse fields of study.

Product Title:PE/Cyanine7 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1277
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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