PE/Cyanine5 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1284)

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SKU:
AGEL1284
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse/Human CD44 Monoclonal Antibody (PE/Cyanine5 Conjugated, IM7) is a versatile tool designed for researchers investigating CD44, a cell surface glycoprotein involved in cell adhesion and migration processes, as well as cell-cell interactions. This monoclonal antibody, conjugated with PE/Cyanine5, is specifically engineered to bind to CD44 in both mouse and human samples, allowing for precise detection and analysis in a variety of experimental settings.CD44 is a multifunctional molecule known to participate in diverse physiological and pathological processes, including lymphocyte activation, tumor metastasis, and inflammation. By targeting CD44, researchers can gain insights into its role in various biological pathways and diseases, making this antibody an invaluable asset for studies in immunology, oncology, and related fields.

With its high reactivity and specificity, the Mouse/Human CD44 Monoclonal Antibody (PE/Cyanine5 Conjugated, IM7) offers researchers a reliable tool for exploring the functional implications of CD44 expression in different cell types and experimental models. Whether investigating immune responses, cancer progression, or tissue regeneration, this antibody provides a powerful means to advance our understanding of CD44 biology and its implications for human health and disease.

Product Title:PE/Cyanine5 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1284
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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