PE/Cyanine5 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1276)

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SKU:
AGEL1276
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse/Human CD44 Monoclonal Antibody PE-Cyanine5 Conjugated (IM7) is a versatile tool for researchers studying CD44, a multifunctional cell surface glycoprotein involved in cell adhesion, migration, and signaling. This monoclonal antibody, conjugated with PE-Cyanine5, allows for simultaneous analysis of CD44 expression and other markers in flow cytometry and fluorescence-activated cell sorting (FACS) experiments.CD44 is known for its diverse roles in various physiological and pathological processes, including inflammation, wound healing, and cancer metastasis. By targeting CD44 with the IM7 antibody, researchers can investigate its expression levels in both mouse and human samples, providing valuable insights into the molecular mechanisms underlying disease progression and immune response regulation.

With its high specificity and sensitivity, the Mouse/Human CD44 Monoclonal Antibody PE-Cyanine5 Conjugated (IM7) is a reliable reagent for studies focusing on the role of CD44 in cancer biology, stem cell research, and immunology. Its ability to bind specifically to CD44 epitopes enhances the accuracy and reliability of experimental data, making it an essential tool for elucidating the complex functions of CD44 in various biological contexts.

Product Title:PE/Cyanine5 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1276
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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