PE/Cyanine5.5 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1286)

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SKU:
AGEL1286
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse/Human CD44 Monoclonal Antibody (PE/Cyanine5.5) IM7 (AGEL1286) is a versatile tool designed for the detection and analysis of CD44, a cell surface glycoprotein involved in cell adhesion, migration, and signaling processes. This monoclonal antibody, conjugated with PE/Cyanine5.5, is suitable for use in flow cytometry applications, enabling precise identification and characterization of CD44-expressing cells in both mouse and human samples.CD44 is a multifunctional molecule implicated in various physiological and pathological processes, including immune response, inflammation, and cancer metastasis. By targeting CD44, researchers can gain insights into its role in cell interactions, tumor progression, and stem cell behavior.

This antibody offers high specificity and sensitivity, allowing for reliable and accurate data generation in studies related to immunology, oncology, and stem cell research.The IM7 monoclonal antibody facilitates the study of CD44 distribution, expression levels, and functional properties in different cell types and tissues, providing valuable information for understanding disease mechanisms and identifying potential therapeutic targets. With its superior performance and broad applicability, this antibody is an essential tool for researchers investigating the complex functions of CD44 in various biological contexts.

Product Title:PE/Cyanine5.5 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1286
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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