PE/Cyanine5.5 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1278)

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SKU:
AGEL1278
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse/Human CD44 Monoclonal Antibody PE-Cyanine5.5 Conjugated (IM7) is a versatile tool for immunological research, designed for the detection and analysis of CD44, a cell surface glycoprotein involved in cell adhesion and migration. This monoclonal antibody, conjugated with PE-Cyanine5.5, is reactive with both mouse and human samples, allowing for cross-species studies.CD44 plays a key role in a variety of physiological processes, including lymphocyte activation, homing, and inflammation. Its expression is also implicated in cancer progression and metastasis.

The IM7 antibody specifically targets CD44, enabling precise identification and localization within different cell types and tissues.By using this antibody, researchers can delve into the complexities of CD44 function in various biological contexts, from immune responses to tumor microenvironments. This tool is valuable for studies focusing on immunology, oncology, and regenerative medicine, offering insights that can shape innovative therapeutic approaches and diagnostic strategies.

Product Title:PE/Cyanine5.5 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1278
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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