Biotin Anti-Human/Mouse CD44 Antibody [IM7] (AGEL0365)

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SKU:
AGEL0365
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rat
Isotype:
IgG2b
Clone:
IM7
Conjugation:
Biotin
Applications:
FC
Frequently bought together:

Description

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Biotin Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse/Human CD44 Monoclonal Antibody (Biotin Conjugated) (IM7) from AssayGenie (AG-EL0365) is a highly specific antibody designed for the detection of CD44, a cell surface glycoprotein involved in cell adhesion and migration. This antibody is conjugated with biotin, allowing for easy and efficient detection in immunoassays such as ELISA and flow cytometry.CD44 plays a crucial role in various cellular processes, including lymphocyte activation, homing, and signaling. Its expression has been linked to cancer metastasis and stem cell function, making it a key molecule of interest in cancer research and regenerative medicine.

By targeting CD44 with this monoclonal antibody, researchers can study its role in different cell types and gain insights into its functions in health and disease.With its high specificity and validated performance in a range of research applications, the Mouse/Human CD44 Monoclonal Antibody (Biotin Conjugated) (IM7) is a valuable tool for scientists investigating CD44 biology and its implications in diverse physiological and pathological contexts. Unlock the potential of CD44 research with this reliable and versatile antibody from AssayGenie.

Product Title:Biotin Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL0365
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Biotin Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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