GenieFluor 488 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL0368)

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SKU:
AGEL0368
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rat
Isotype:
IgG2b
Clone:
IM7
Conjugation:
AF 488
Applications:
FC
Frequently bought together:

Description

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GenieFluor 488 Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse/Human CD44 Monoclonal Antibody (AGEL0368) offered by AssayGenie is a versatile tool for researchers studying CD44, a cell surface glycoprotein involved in cell adhesion and migration processes. This monoclonal antibody is conjugated with Alexa Fluor 488, facilitating fluorescence-based detection and analysis in both mouse and human samples.CD44 is a multifunctional molecule with key roles in cell-cell interactions, lymphocyte activation, and tumor metastasis. By targeting CD44 with this high-quality antibody, researchers can investigate its expression levels and localization in various cell types, providing insights into its function in physiological and pathological processes.

The ability to detect CD44 in both mouse and human samples enhances the antibody's utility in comparative studies and translational research efforts.With its specificity and sensitivity, the Mouse/Human CD44 Monoclonal Antibody (AGEL0368) from AssayGenie is a valuable resource for studies focusing on cell adhesion, cancer biology, and immune responses involving CD44. Researchers can rely on this antibody to accurately detect and analyze CD44 expression, contributing to a deeper understanding of its impact on cellular behavior and disease progression.

Product Title:GenieFluor 488 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL0368
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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