GenieFluor 488 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1288)

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SKU:
AGEL1288
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
IM7
Conjugation:
AF 488
Frequently bought together:

Description

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GenieFluor 488 Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse Human CD44 Monoclonal Antibody (AF488 Conjugated, IM7) from AssayGenie (Product Code: AGL1288) is a powerful tool for researchers studying CD44 expression in mouse and human samples. This monoclonal antibody is conjugated with AF488, making it fluorescent for easy detection in various experimental techniques.CD44 is a multifunctional cell surface glycoprotein involved in cell adhesion, migration, and signaling. It plays a crucial role in various physiological and pathological processes, including immunity, inflammation, and cancer progression. The IM7 monoclonal antibody is highly specific to CD44, allowing for precise detection and analysis of this important molecule.

With its dual reactivity towards mouse and human CD44, researchers can confidently use this antibody in a wide range of applications, such as flow cytometry, immunofluorescence, and immunohistochemistry. The AF488 conjugation enhances the antibody's versatility and compatibility with fluorescence detection systems, making it an excellent choice for studies in immunology, oncology, and stem cell research.By utilizing the Mouse Human CD44 Monoclonal Antibody (AF488 Conjugated, IM7), researchers can gain valuable insights into the role of CD44 in health and disease, paving the way for innovative discoveries and potential therapeutic interventions.

Product Title:GenieFluor 488 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1288
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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