PerCP Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL1107)

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SKU:
AGEL1107
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
M1/70
Conjugation:
PerCP
Frequently bought together:

Description

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PerCP Anti-Mouse/Human CD11b Antibody [M1/70]

The Mouse/Human CD11b Monoclonal Antibody (PerCP Conjugated, M1/70) is a versatile tool designed for researchers studying immune cells expressing the CD11b antigen. This antibody, conjugated with PerCP, provides a convenient method for flow cytometry analysis of CD11b in both mouse and human samples. The M1/70 antibody specifically recognizes the CD11b protein, allowing for precise identification and quantification of myeloid cells such as monocytes, macrophages, and granulocytes.CD11b, also known as integrin alpha M, is a key cell surface receptor involved in various immune functions, including cell adhesion, migration, and phagocytosis. Its expression on myeloid cells is essential for mediating inflammatory responses and immune cell activation. Studying CD11b expression can provide insights into the role of myeloid cells in inflammation, infection, and immune-related diseases.

This monoclonal antibody is a valuable tool for research in immunology, inflammation, and cancer biology. By accurately detecting and quantifying CD11b-expressing cells, researchers can gain a deeper understanding of the immune response in different physiological and pathological conditions. The PerCP conjugation of the M1/70 antibody enhances its utility for flow cytometry applications, enabling precise and high-resolution analysis of CD11b-positive cells in complex samples.Overall, the Mouse/Human CD11b Monoclonal Antibody (PerCP Conjugated, M1/70) offers researchers a reliable and sensitive reagent for investigating the role of CD11b-expressing cells in immune responses and disease pathogenesis. Its specificity, versatility, and compatibility with flow cytometry make it a valuable asset for advancing research in immunology and related fields.

Product Title:PerCP Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL1107
Size:25µg, 100µg
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PerCP Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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