PerCP Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL0309)

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SKU:
AGEL0309
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rat
Isotype:
IgG2b
Clone:
M1/70
Conjugation:
PerCP
Applications:
FC
Frequently bought together:

Description

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PerCP Anti-Mouse/Human CD11b Antibody [M1/70]

The CD11b Monoclonal Antibody (PERCP conjugated, clone M1/70) is a powerful tool for researchers studying the CD11b protein, a cell surface receptor involved in various immune responses. This monoclonal antibody, conjugated with PERCP for flow cytometry applications, is highly specific to both mouse and human CD11b, offering versatility in experimental settings.CD11b, also known as integrin alpha M, is a key marker for myeloid cells, including monocytes, macrophages, and granulocytes. Its role in cell adhesion, migration, and phagocytosis makes it a crucial target for immunology and inflammation studies. The monoclonal antibody M1/70 binds specifically to CD11b, enabling precise detection and characterization of these cell populations in a range of samples.

Research involving CD11b is essential for understanding immune responses in both health and disease, including infection, inflammation, and cancer. By using this monoclonal antibody, researchers can unravel the complex interactions and functions of CD11b-expressing cells, paving the way for the development of novel therapeutic strategies targeting these immune components.This CD11b Monoclonal Antibody (PERCP conjugated, clone M1/70) is a reliable tool for investigating the role of CD11b in diverse biological contexts, providing valuable insights into immune cell function and potential therapeutic interventions.

Product Title:PerCP Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL0309
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PerCP Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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