PE/Cyanine5.5 Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL1110)

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SKU:
AGEL1110
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse/Human CD11b Antibody [M1/70]

The Mouse-Human CD11b Monoclonal Antibody (PE-Cyanine5.5 Conjugated, M1/70) is a versatile tool for researchers studying immune cells and inflammation. This monoclonal antibody, available from Assay Genie, is specifically designed for detecting the CD11b protein, a cell surface marker found on myeloid cells like monocytes, macrophages, and granulocytes.CD11b is a key molecule involved in cell adhesion and migration, playing a crucial role in the immune response and inflammatory processes. The M1/70 antibody is conjugated with PE-Cyanine5.5, enabling easy detection by flow cytometry or fluorescence microscopy. This allows for precise identification and analysis of CD11b-expressing cells in various biological samples.

By targeting CD11b, researchers can investigate the role of myeloid cells in immune function, inflammation, and disease progression. Understanding the behavior and function of these cells, particularly in the context of conditions like infection, autoimmunity, and cancer, can provide valuable insights for developing novel therapeutic strategies.Overall, the Mouse-Human CD11b Monoclonal Antibody (PE-Cyanine5.5 Conjugated, M1/70) from Assay Genie is a valuable resource for immunologists, cell biologists, and researchers interested in unraveling the complexities of the immune system and inflammatory responses.

Product Title:PE/Cyanine5.5 Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL1110
Size:25µg, 100µg
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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