Mouse Granzyme B(G,H)/GZMB Recombinant Protein (RPES0956)
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- SKU:
- RPES0956
- Product type:
- Recombinant Protein
- Host species:
- Human Cells
- Reactivity:
- Mouse
Frequently bought together:
Description
system_update_alt데이터시트
Mouse Granzyme B(G,H)/GZMB Recombinant Protein
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
| Product Name: | Mouse Granzyme B(G,H)/GZMB Recombinant Protein (RPES0956) |
| Product Code: | RPES0956 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | Granzyme B(G,H),CTLA-1,Cytotoxic cell protease 1,CCP1,Fragmentin-2,Gzmb,Ctla-1, Ctla1 |
| Accession: | P04187 |
| Sequence: | Gly19-Ser247 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 85 % as determined by SDS-PAGE |
| Mol Mass: | 26.5 kDa |
| AP Mol Mass: | 35kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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