The Mouse GR-1 Monoclonal Antibody FITC Conjugated (RB6-8C5) is a versatile tool for researchers working in immunology and cell biology. This antibody is specifically designed to target the GR-1 antigen, which is a surface marker expressed on cells of the myeloid lineage, including neutrophils and inflammatory monocytes. With its FITC conjugation, this antibody allows for easy visualization and detection of GR-1-expressing cells in flow cytometry and immunofluorescence applications. The RB6-8C5 antibody has been extensively validated for use in mouse samples, ensuring reliable and consistent results in experimental studies.The GR-1 antigen is known for its role in immune responses, particularly in the context of inflammation and infection.
By specifically targeting GR-1, researchers can gain valuable insights into the dynamics of myeloid cell populations and their involvement in various physiological and pathological processes. Whether studying immune cell dynamics in infectious diseases, inflammation, or cancer, this antibody provides a valuable tool for probing the functions of GR-1-expressing cells.Overall, the Mouse GR-1 Monoclonal Antibody FITC Conjugated (RB6-8C5) offers a reliable and specific reagent for investigating myeloid cell populations in mouse models, contributing to the advancement of research in immunology and related fields.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35461 P0CW03
Gene ID:
546644 ,17067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.
![FITC Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL0462)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/608x608/products/120748/118928/fitc-anti-mouse-ly-6gly-6c-gr-1-antibody-rb6-8c5-agel0462__00989__37123.1732013324.jpg?c=1 "FITC Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL0462)")
![FITC Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL0462)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/1280x1280/products/120748/118928/fitc-anti-mouse-ly-6gly-6c-gr-1-antibody-rb6-8c5-agel0462__00989__37123.1732013324.jpg?c=1&imbypass=on "FITC Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL0462)")
![Biotin Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL0461)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/120747/118927/biotin-anti-mouse-ly-6gly-6c-gr-1-antibody-rb6-8c5-agel0461__11524__01569.1732013323.jpg?c=1 "Biotin Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL0461)")
![Purified Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL0460)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/120746/118926/anti-mouse-ly-6gly-6c-gr-1-antibody-rb6-8c5-agel0460__86006__55537.1732013322.jpg?c=1 "Purified Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL0460)")
