FITC Anti-Mouse Fc?RI? Antibody [MAR-1] (AGEL1984)

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SKU:
AGEL1984
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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FITC Anti-Mouse FcεRIα Antibody [MAR-1]

The Mouse FC Epsilon RI Alpha Monoclonal Antibody (FITC Conjugated, MAR-1, AGEL1984) offered by AssayGenie is a valuable tool for researchers studying immune responses and allergic reactions in mice. This antibody specifically targets the FC Epsilon RI Alpha protein, which is a key player in the immune system's response to allergens and immunoglobulin E (IgE).With its FITC conjugation, this monoclonal antibody allows for easy and sensitive detection of FC Epsilon RI Alpha in various cell types and tissues, making it ideal for immunology studies and allergy research. By enabling the visualization and analysis of FC Epsilon RI Alpha expression, researchers can gain insights into the mechanisms underlying allergic responses and immune system activation in mouse models.

The MAR-1 antibody has been rigorously validated for use in various experimental techniques, including flow cytometry, immunofluorescence, and immunohistochemistry, ensuring reliable and reproducible results. Its high specificity and sensitivity make it a valuable tool for investigating the role of FC Epsilon RI Alpha in allergic diseases, asthma, and other immune-related conditions in mouse models.For researchers looking to deepen their understanding of immune responses and allergic reactions in mice, the Mouse FC Epsilon RI Alpha Monoclonal Antibody (FITC Conjugated, MAR-1, AGEL1984) from AssayGenie is a trusted and effective choice.

Product Title:FITC Anti-Mouse FcεRIα Antibody [MAR-1]
SKU:AGEL1984
Size:25µg, 100µg
Clone No:MAR-1
Synonyms:High affinity immunoglobulin epsilon receptor subunit alpha;Fc-epsilon RI-alpha;FcERI;Fcer1a;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:FITC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P20489
Gene ID:14125
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

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