PE/Cyanine5.5 Anti-Mouse F4/80 Antibody [CI:A3-1] (AGEL0563)

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SKU:
AGEL0563
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse F4/80 Antibody [CI:A3-1]

The Mouse F4/80 Monoclonal Antibody PE/Cyanine5.5 Conjugated (CI-A3-1) is a powerful tool for researchers studying macrophages, a key component of the immune system responsible for phagocytosis and immune response regulation. This antibody, conjugated with both PE and Cyanine5.5 fluorophores, allows for bright and efficient detection of the F4/80 protein in mouse samples using flow cytometry or fluorescence microscopy.F4/80, a well-established macrophage marker, is crucial for identifying and studying macrophages in various tissues and disease models. By targeting F4/80, researchers can gain insights into the role of macrophages in inflammation, tissue repair, and disease pathogenesis.

This antibody specifically recognizes the F4/80 antigen, enabling precise labeling and analysis of macrophage populations in complex biological samples.With its high specificity and sensitivity, the Mouse F4/80 Monoclonal Antibody PE/Cyanine5.5 Conjugated (CI-A3-1) is a valuable asset for immunologists, cell biologists, and researchers investigating the intricate functions of macrophages in health and disease. Its versatility and reliability make it an essential reagent for advancing knowledge in immunology, inflammation, and therapeutic development.

Product Title:PE/Cyanine5.5 Anti-Mouse F4/80 Antibody [CI:A3-1]
SKU:AGEL0563
Size:50 Tests, 100 Tests, 200 Tests
Clone No:CI:A3-1
Synonyms:Adhesion G protein-coupled receptor E1;Adgre1;Cell surface glycoprotein F4/80;EGF-like module receptor 1;Adgre1;Emr1; Gpf480;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q61549
Gene ID:13733
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

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