Mouse Ephrin-A5/EFNA5 Recombinant Protein (RPES0514)
- SKU:
- RPES0514
- Product type:
- Recombinant Protein
- Host species:
- Human Cells
- Reactivity:
- Mouse
Frequently bought together:
Description
system_update_alt데이터시트
Mouse Ephrin-A5/EFNA5 Recombinant Protein
Ephrin-A5 is a glycosylphosphatidylinositol (GPI)-anchored protein of the ephrin-A subclass of ephrin ligands that binds to the EphA subclass of Eph receptors. Ephrin-A5 has also been shown to bind to the EphB2 receptor. It is crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-A5 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.
| Product Name: | Mouse Ephrin-A5/EFNA5 Recombinant Protein (RPES0514) |
| Product Code: | RPES0514 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | Ephrin-A5, AL-1, EPH-related receptor tyrosine kinase ligand 7, Epl7, Eplg7, Lerk7, Efna5, |
| Accession: | O08543 |
| Sequence: | Gln21-Gln206 |
| Fusion tag: | C-6His |
| Activity: | Immobilized Human EphA8-Fc(Cat: PKSH032386) at 1.5µg/ml(100 ?l/well) can bind Human EFNA5-His. The ED50 of EFNA5-His is 12.63ug/ml . |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Ephrin-A5 is produced by our Mammalian expression system and the target gene encoding Gln21-Gln206 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90 % as determined by SDS-PAGE |
| Mol Mass: | 22.5 kDa |
| AP Mol Mass: | 25-28kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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