Mouse Cyclophilin B Recombinant Protein (RPPB1537)
- SKU:
- RPPB1537
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Mouse
- Target:
- Cyclophilin B
- Synonyms:
- Peptidyl-prolyl cis-trans isomerase B
- PPIase B
- CYP-S1
- Cyclophilin B
- Source:
- Escherichia Coli
- Uniprot:
- P24369
Frequently bought together:
Description
Product Name: | Mouse Cyclophilin B Recombinant Protein |
Product Code: | RPPB1537 |
Size: | 10µg |
Species: | Mouse |
Target: | Cyclophilin B |
Synonyms: | Peptidyl-prolyl cis-trans isomerase B, PPIase B, CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin, SCYLP. |
Source: | Escherichia Coli |
Physical Appearance: | Sterile filtered colorless solution. |
Formulation: | Cyclophilin B protein solution (1mg/ml) containing Phosphate Buffered Saline (pH7.4) and 10% glycerol. |
Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Purity: | Greater than 95.0% as determined by SDS-PAGE. |
Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMNDKKKG PKVTVKVYFD LQIGDESVGR VVFGLFGKTV PKTVDNFVAL ATGEKGFGYK NSKFHRVIKD FMIQGGDFTR GDGTGGKSIY GERFPDENFK LKHYGPGWVS MANAGKDTNG SQFFITTVKT SWLDGKHVVF GKVLEGMDVV RKVESTKTDSRDKPLKDVII VDSGKIEVEK PFAIAKE |
Biological Activity: | Specific activity is > 1,000 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAFP-PNA per minute at 37C in Tris–HCl pH 8.0 using chymotrypsin. |
Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.
Cyclophilin B Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 207 amino acids (34-216 a.a) and having a molecular mass of 22.7kDa.Cyclophilin B is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
UniProt Protein Function: | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
UniProt Code: | P24369 |
NCBI GenInfo Identifier: | 215273926 |
NCBI Gene ID: | 19035 |
NCBI Accession: | P24369.2 |
UniProt Related Accession: | P24369 |
Molecular Weight: | 23,713 Da |
NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase B |
NCBI Synonym Full Names: | peptidylprolyl isomerase B |
NCBI Official Symbol: | Ppib |
NCBI Official Synonym Symbols: | Cphn2; Cphn-2; CyP-20b; AA408962; AA553318; AI844835 |
NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase B |
UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase B |
UniProt Synonym Protein Names: | CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP |
Protein Family: | Probable peptidyl-prolyl cis-trans isomerase |
UniProt Gene Name: | Ppib |