Mouse CRP Recombinant Protein (RPPB3265)
- SKU:
- RPPB3265
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Mouse
- Target:
- CRP
- Synonyms:
- C-reactive protein
- pentraxin-related
- Crp
- Source:
- Sf9 Insect cells
- Uniprot:
- P14847
Description
| Product Name: | Mouse CRP Recombinant Protein |
| Product Code: | RPPB3265 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | CRP |
| Synonyms: | C-reactive protein, pentraxin-related, Crp. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | CRP solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M PMSF and 40% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | HEDMFKKAFV FPKESDTSYV SLEAESKKPL NTFTVCLHFY TALSTVRSFS VFSYATKKNS NDILIFWNKD KQYTFGVGGA EVRFMVSEIP EAPTHICASW ESATGIVEFW IDGKPKVRKS LHKGYTVGPD ASIILGQEQD SYGGDFDAKQ SLVGDIGDVN MWDFVLSPEQ ISTVYVGGTL SPNVLNWRAL NYKAQGDVFI KPQLWSLEHH HHHH |
C-Reactive Protein or CRP, is a protein, part of the pentraxin superfamily. Among the protein’s activities, CRP can promote agglutination, swelling of the bacteria capsule, phagocytosis etc. this protein can also cause complement fixation via a calcium-dependent binding to the molecule phosphorylcholine.
CRP Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 214 amino acids (20-225 a.a) and having a molecular mass of 24.1 kDa.CRP is fused to a 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Cellular Component: extracellular space; growth cone; extracellular region; filopodium Molecular Function:protein homodimerization activity; low-density lipoprotein receptor binding; metal ion binding; complement component C1q binding; low-density lipoprotein binding; cholesterol binding; calcium ion binding Biological Process: protein polymerization; positive regulation of nitric oxide biosynthetic process; negative regulation of vasodilation; wound healing; positive regulation of superoxide release; acute-phase response; negative regulation of superoxide release; complement activation, classical pathway |
| UniProt Code: | P14847 |
| NCBI GenInfo Identifier: | 408360035 |
| NCBI Gene ID: | 12944 |
| NCBI Accession: | P14847.2 |
| UniProt Secondary Accession: | P14847,E9PZ20, |
| UniProt Related Accession: | P14847 |
| Molecular Weight: | 25,360 Da |
| NCBI Full Name: | C-reactive protein |
| NCBI Synonym Full Names: | C-reactive protein, pentraxin-related |
| NCBI Official Symbol: | Crp |
| NCBI Official Synonym Symbols: | AI255847 |
| NCBI Protein Information: | C-reactive protein; C-reactive protein, petaxin related |
| UniProt Protein Name: | C-reactive protein |
| Protein Family: | Cryparin |
| UniProt Gene Name: | Crp |
| UniProt Entry Name: | CRP_MOUSE |
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