Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one?peptidase S1 domain. Coagulation factor IX / F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX / F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX / F9 are also the cause of recessive X-linked hemophilia B ( HEMB ) which also known as Christmas disease.
Product Name:
Mouse Coagulation Factor F9 Recombinant Protein (RPES2933)
Product Code:
RPES2933
Size:
10µg
Species:
Mouse
Expressed Host:
HEK293 Cells
Synonyms:
AW111646,Cf-9,Cf9
Accession:
P16294
Sequence:
Met 1-Thr 471
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the full length of mouse F9 (P16294) (Met 1-Thr 471) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
Purity:
> 95 % as determined by SDS-PAGE
Mol Mass:
51.3 kDa
AP Mol Mass:
60-80 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
