The Mouse CD90.2 Monoclonal Antibody (PE-conjugated, 30H12) is a critical tool for researchers studying mouse CD90.2, also known as Thy1.2. This monoclonal antibody, conjugated to phycoerythrin (PE), offers high specificity and sensitivity for detecting CD90.2 expression on the surface of mouse cells.CD90.2, a glycosylphosphatidylinositol-anchored protein, is commonly used as a marker for various cell types, including stem cells, T cells, and neuronal cells. Its involvement in cell adhesion, migration, and signal transduction processes makes it a key molecule in developmental biology and immunology research.By utilizing the Mouse CD90.2 Monoclonal Antibody (PE-conjugated, 30H12) in flow cytometry, immunofluorescence, or immunohistochemistry assays, researchers can accurately identify and characterize CD90.
2-positive cells within complex cellular populations. This antibody's reliability and versatility make it an indispensable tool for investigations into cell differentiation, tissue regeneration, and immunological responses in mouse models.Unlock the potential of your research by incorporating the Mouse CD90.2 Monoclonal Antibody (PE-conjugated, 30H12) into your experimental workflow. This antibody provides valuable insights into the role of CD90.2 in diverse biological processes, paving the way for innovative discoveries and advancements in fields such as stem cell biology, immunotherapy, and neurobiology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
21838
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.