The Mouse CD90.2 Monoclonal Antibody (FITC-conjugated, 30-H12, AGEL1212) is a powerful tool designed for researchers studying CD90.2 expression in mouse samples. CD90.2, also known as Thy-1.2, is a glycosylphosphatidylinositol-anchored cell surface antigen widely used as a marker for various cell types, including stem cells and lymphocytes.This monoclonal antibody, labeled with FITC for fluorescent detection, specifically targets CD90.2, allowing for accurate and sensitive identification in flow cytometry and immunofluorescence applications.
Its high specificity and low background make it suitable for isolating and analyzing CD90.2-positive cells with precision and reliability.Researchers in immunology, stem cell biology, and cancer research will find the Mouse CD90.2 Monoclonal Antibody indispensable for pursuing studies related to cell characterization, differentiation, and functional analysis. Its versatility and robust performance make it a valuable asset for investigating the role of CD90.2 in various biological processes and disease models.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
21838
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.