The Mouse CD90.2 Monoclonal Antibody (Biotin Conjugated, 30-H12) is an essential tool for researchers studying CD90.2, a cell surface glycoprotein commonly used as a marker for T cell subsets, including memory T cells and regulatory T cells. This monoclonal antibody, conjugated with biotin for enhanced detection and versatility, is specifically designed for use in immunoassays and flow cytometry applications.CD90.2, also known as Thy1.2, is a widely recognized marker for various T cell populations and has been implicated in immune response regulation and T cell activation. By targeting CD90.2 with high specificity, this antibody allows for precise identification and analysis of T cell subsets in different experimental settings.
Its reliable performance and sensitivity make it an indispensable tool for researchers in immunology, cancer biology, and vaccine development.With the Mouse CD90.2 Monoclonal Antibody (Biotin Conjugated, 30-H12), researchers can explore the intricate interactions of T cell populations, investigate immune responses in diverse contexts, and advance our understanding of T cell-mediated immunity. This antibody opens up avenues for innovative research in immunotherapy, autoimmune diseases, infectious diseases, and beyond, offering valuable insights into the complex mechanisms underlying T cell function and immune regulation.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Gene ID:
21838
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.