The Mouse CD90.1 Monoclonal Antibody (19E12) is a specialized tool for researchers studying CD90.1, a cell surface antigen commonly used as a marker for identifying specific cell populations, such as stem cells and lymphocytes, in mouse models. This monoclonal antibody, clone 19E12, is highly specific and sensitive, allowing for accurate detection and analysis of CD90.1 expression in various tissues and cell types.CD90.1, also known as Thy1.1, is a well-characterized glycoprotein involved in cell-cell adhesion, signal transduction, and immune response modulation. Its presence on certain cell populations has been linked to various physiological and pathological processes, making it a valuable target for research in immunology, stem cell biology, and cancer biology.
Researchers can use this antibody for techniques such as flow cytometry, immunohistochemistry, and Western blotting to uncover the role of CD90.1 in different biological contexts.This Monoclonal Antibody (19E12) offers reliable and reproducible results, enabling scientists to gain valuable insights into the function and behavior of CD90.1-positive cells in experimental settings. By facilitating the identification and characterization of these cell populations, this antibody supports advancements in understanding immune responses, cellular differentiation, and disease mechanisms in mouse models.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90.1 is a 25-35 kD immunoglobulin superfamily member, also known as Thy-1. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells. CD90.1 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.1 is involved in costimulation of lymphocyte proliferation and activation, and hematopoietic stem cell differentiation. CD90.1 has been shown to interact with CD45.
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