PerCP Anti-Mouse CD8a Antibody [53-6.7] (AGEL1339)

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SKU:
AGEL1339
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
53-7.6
Conjugation:
PerCP
Frequently bought together:

Description

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PerCP Anti-Mouse CD8a Antibody [53-6.7]

The Mouse CD8a Monoclonal Antibody (PERCP conjugated, 53.7.6) is a specialized tool designed for precise and reliable detection of the CD8a cell surface marker in mouse samples. This monoclonal antibody, clone 53.7.6, is conjugated to PERCP, enhancing its fluorescence signal for flow cytometry applications, providing researchers with a powerful tool for immune cell analysis.CD8a, a marker of cytotoxic T cells, plays a crucial role in immune responses by identifying and eliminating intracellular pathogens and abnormal cells. The highly specific binding of the 53.7.6 monoclonal antibody to CD8a enables researchers to accurately identify and quantify CD8a-expressing cells in various immune cell populations, aiding in immunophenotyping studies and immune response characterization.

With its superior specificity and sensitivity, the Mouse CD8a Monoclonal Antibody (PERCP conjugated, 53.7.6) from AssayGenie is an essential reagent for immunology research, vaccine development, and studies focusing on T cell biology and immune dysfunction. Unlock the potential of your research by utilizing this high-quality antibody for precise identification and analysis of CD8a-expressing cells in mouse models, advancing our understanding of immune responses and paving the way for innovative therapeutic strategies.

Product Title:PerCP Anti-Mouse CD8a Antibody [53-6.7]
SKU:AGEL1339
Size:25µg, 100µg
Clone No:53-6.7
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PerCP Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P01731
Gene ID:12525
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

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