PE/Cyanine7 Anti-Mouse CD86 Antibody [GL-1] (AGEL0547)

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SKU:
AGEL0547
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD86 Antibody [GL-1]

The Mouse CD86 Monoclonal Antibody (PE/Cyanine7 Conjugated) is a vital tool for researchers studying immune responses and cell signaling pathways. This antibody, designated as GL-1, specifically targets CD86, a crucial co-stimulatory molecule expressed on antigen-presenting cells.CD86 plays a key role in immune activation by providing essential signals to T cells during antigen presentation. By binding to CD86, the antibody enables the detection and analysis of this important protein in various cell types, making it invaluable for immunology research, vaccine development, and studies on autoimmune diseases.The PE/Cyanine7 conjugation facilitates multi-color flow cytometry applications, allowing for precise and reliable identification of CD86-expressing cells within a complex cell population.

With its high specificity and sensitivity, this antibody provides researchers with a powerful tool to investigate the mechanisms underlying immune responses and the development of immunotherapies.The Mouse CD86 Monoclonal Antibody (PE/Cyanine7 Conjugated) is a reliable reagent that enhances the understanding of immune regulation and interaction, offering valuable insights into potential therapeutic targets for a range of immune-related disorders.

Product Title:PE/Cyanine7 Anti-Mouse CD86 Antibody [GL-1]
SKU:AGEL0547
Size:50 Tests, 100 Tests, 200 Tests
Clone No:GL-1
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42082
Gene ID:12524
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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