PE/Cyanine5.5 Anti-Mouse CD86 Antibody [GL-1] (AGEL0548)

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SKU:
AGEL0548
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD86 Antibody [GL-1]

The Mouse CD86 Monoclonal Antibody (PE/Cyanine5.5 Conjugated, GL-1) is a powerful tool for studying immune responses and cell-cell interactions in research settings. This antibody, specifically designed for detecting CD86, a critical co-stimulatory molecule involved in T cell activation and immune regulation, is conjugated with PE/Cyanine5.5 for easy detection and analysis.CD86, also known as B7-2, plays a key role in the activation of T cells by binding to CD28, providing the secondary signal necessary for T cell activation and proliferation. Research involving CD86 is vital in understanding the mechanisms of immune response regulation, autoimmunity, and infection. This monoclonal antibody, derived from mouse cell lines, offers high specificity and sensitivity in immunofluorescence assays, flow cytometry, and other experimental techniques.

By targeting CD86, researchers can delve deeper into the intricate pathways of immune system activation and modulation. This antibody enables precise identification and quantification of CD86 expression on various cell populations, shedding light on the complex interactions that govern immune responses. Its versatility and reliability make it an invaluable tool for investigations into immunology, vaccine development, and inflammatory diseases.Unlock the potential of your research with the Mouse CD86 Monoclonal Antibody (PE/Cyanine5.5 Conjugated, GL-1) and gain insights into the dynamic world of immune regulation and cellular communication.

Product Title:PE/Cyanine5.5 Anti-Mouse CD86 Antibody [GL-1]
SKU:AGEL0548
Size:50 Tests, 100 Tests, 200 Tests
Clone No:GL-1
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42082
Gene ID:12524
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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