PE/Cyanine5.5 Anti-Mouse CD80 Antibody [16-10A1] (AGEL0537)

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SKU:
AGEL0537
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD80 Antibody [16-10A1]

The Mouse CD80 Monoclonal Antibody PE/Cyanine5.5 Conjugated (16-10A1) is a powerful tool for researchers studying immune responses and cell signaling pathways. This antibody, available from Assay Genie, is specifically designed to target CD80, a critical co-stimulatory molecule involved in T cell activation and immune regulation.By utilizing the 16-10A1 antibody conjugated with PE/Cyanine5.5, scientists can easily detect and analyze CD80 expression in various cell types using flow cytometry or fluorescent microscopy. This high-quality antibody provides reliable results and is ideal for experiments focusing on immune cell interactions, inflammation, and autoimmune diseases.

CD80, also known as B7-1, plays a key role in modulating T cell function and promoting immune responses. Understanding its expression and activity is essential for unraveling the complexities of immune regulation and developing targeted therapies for conditions such as cancer, autoimmune disorders, and infectious diseases.Researchers can trust the Mouse CD80 Monoclonal Antibody PE/Cyanine5.5 Conjugated (16-10A1) from Assay Genie for accurate and reproducible results in their immunology and cell biology studies. Gain valuable insights into immune system function and discover new pathways for therapeutic intervention with this innovative antibody tool.

Product Title:PE/Cyanine5.5 Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL0537
Size:25µg, 100µg
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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