APC Anti-Mouse CD80 Antibody [16-10A1] (AGEL0534)

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SKU:
AGEL0534
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
16-10A1
Conjugation:
APC
Frequently bought together:

Description

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APC Anti-Mouse CD80 Antibody [16-10A1]

The Mouse CD80 Monoclonal Antibody (APC-conjugated 16-10A1) offered by Assay Genie is a potent tool for researchers investigating immune responses and molecular interactions involving CD80. This antibody is specifically designed to target CD80, a critical co-stimulatory molecule involved in T cell activation and immune regulation. By utilizing the APC-conjugated 16-10A1 antibody, researchers can easily detect and analyze CD80 expression in various cell types, providing valuable insights into immune system function and potential therapeutic targets. With its high reactivity and specificity, this antibody is a reliable choice for flow cytometry and other experimental applications. CD80, also known as B7-1, plays a key role in initiating and regulating immune responses, making it a key player in conditions such as autoimmunity, transplantation, and infectious diseases.

Understanding the function of CD80 is essential for developing targeted therapies and immunotherapies that modulate immune responses effectively.Overall, the Mouse CD80 Monoclonal Antibody (APC-conjugated 16-10A1) is a valuable asset for researchers aiming to elucidate the mechanisms of immune regulation and develop novel treatments for immune-related disorders. By providing accurate and reliable detection of CD80, this antibody contributes to advancements in immunology, cancer research, and drug development.

Product Title:APC Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL0534
Size:25µg, 100µg
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:APC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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