Mouse CD80/B7 Recombinant Protein (RPES2320)
- SKU:
- RPES2320
- Product type:
- Recombinant Protein
- Host species:
- Human Cells
- Reactivity:
- Mouse
Frequently bought together:
Description
system_update_alt데이터시트
Mouse CD80/B7 Recombinant Protein
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.
Product Name: | Mouse CD80/B7 Recombinant Protein (RPES2320) |
Product Code: | RPES2320 |
Size: | 10µg |
Species: | Mouse |
Expressed Host: | Human Cells |
Synonyms: | T-lymphocyte activation antigen CD80, Activation B7-1 antigen, B7, CD80,Cd28l,Ly-53,Ly53,MIC17,TSA1 |
Accession: | Q00609 |
Sequence: | Val38-Lys245 |
Fusion tag: | C-Fc |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Mouse B7-1 antigen is produced by our Mammalian expression system and the target gene encoding Val38-Lys245 is expressed with a Fc tag at the C-terminus. |
Purity: | > 95% as determined by reducing SDS-PAGE. |
Mol Mass: | 50.8 kDa |
AP Mol Mass: | 72 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |