The Mouse CD73 Monoclonal Antibody (FITC Conjugated, TY-23) is a cutting-edge tool designed for researchers investigating CD73, a key cell surface enzyme involved in immune response modulation and regulation of inflammation. This monoclonal antibody, conjugated with FITC for enhanced detection capabilities, is specifically tailored for use in flow cytometry and fluorescence microscopy applications, providing precise and reliable detection of CD73 expression in mouse samples.CD73, also known as ecto-5'-nucleotidase, plays a pivotal role in immune cell function by catalyzing the conversion of extracellular adenosine monophosphate (AMP) to adenosine, a crucial mediator of immune responses. The expression and activity of CD73 have been implicated in various pathological conditions, including cancer, autoimmune diseases, and inflammatory disorders.
By targeting CD73, researchers can gain valuable insights into immune regulation mechanisms and explore potential therapeutic strategies for managing immune-related diseases.This FITC-conjugated monoclonal antibody, clone TY-23, offers high specificity and sensitivity in detecting CD73 expression, making it an invaluable tool for studying the role of CD73 in immune modulation and disease pathogenesis. With its reliable performance and versatility in various experimental settings, the Mouse CD73 Monoclonal Antibody (FITC Conjugated, TY-23) is a must-have for researchers aiming to unravel the complex interplay between CD73 and immune responses in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q61503
Gene ID:
23959
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD73 (ecto-5`-nucleotidase) is a 69 kD GPI-anchored surface protein. In mice, expression of CD73 in bone marrow is restricted to CD11b+ myeloid cells. In spleen, it is largely expressed on T cells.