The Mouse CD71 Monoclonal Antibody (R17-217-1-3) is a vital tool for researchers studying CD71, a transmembrane glycoprotein involved in cellular iron uptake and proliferation. This antibody, generated from mouse hybridoma cells, exhibits high specificity and sensitivity for detecting CD71 expression in various experimental settings.CD71, also known as transferrin receptor protein 1, plays a crucial role in regulating iron homeostasis and cell growth, making it a key target in studies related to cell proliferation, iron metabolism, and cancer biology. By targeting CD71, researchers can investigate its involvement in iron uptake mechanisms, cellular signaling pathways, and potential therapeutic strategies for diseases associated with dysregulated iron metabolism.
With its ability to efficiently recognize and bind to CD71, the Mouse CD71 Monoclonal Antibody enables precise detection and analysis of CD71 expression in different cell types and tissues. Whether used in flow cytometry, immunofluorescence, or immunohistochemistry assays, this antibody facilitates detailed exploration of CD71 function and its implications in various research areas, including oncology, immunology, and metabolic disorders. Unlock the potential of CD71 research with the reliable performance of the Mouse CD71 Monoclonal Antibody (R17-217-1-3) from AssayGenie.
Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Purified Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Unconjugated
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.